5/7/2025
Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 3 Researches
8.3
USERS' SCORE
Good
Based on 6 Reviews
8.3
Supplement Facts
Serving Size: 1 Vegetable Capsule
Amount Per Serving
%DV
Vitamin C (as L-ascorbic acid)
1,000 mg
1,111%
Top Medical Research Studies
9
We investigated how an ascorbic acid-based solution could help treat recurrent cold sores, also known as mucocutaneous herpes. This study was carefully designed as a randomized, double-blind, placebo-controlled trial, which helps ensure the results are reliable and trustworthy.
Participants used a strong solution of Ascoxal, rich in vitamin C, applied to their cold sores multiple times on the first day of the outbreak. We monitored various symptoms daily, including the severity of scabs, redness, and blisters, comparing the experiences of those using the vitamin C solution to a placebo group.
Our findings were promising: the active treatment resulted in fewer days with scabbing and less severe symptoms overall. Moreover, those using the vitamin C solution showed reduced persistence of scabs compared to the placebo group, along with a lower frequency of detected herpes virus after treatment.
In conclusion, this brief course of vitamin C treatment appears to have significant clinical benefits against cold sores, opening the door for future research on more extensive and frequent treatment regimes.
Participants used a strong solution of Ascoxal, rich in vitamin C, applied to their cold sores multiple times on the first day of the outbreak. We monitored various symptoms daily, including the severity of scabs, redness, and blisters, comparing the experiences of those using the vitamin C solution to a placebo group.
Our findings were promising: the active treatment resulted in fewer days with scabbing and less severe symptoms overall. Moreover, those using the vitamin C solution showed reduced persistence of scabs compared to the placebo group, along with a lower frequency of detected herpes virus after treatment.
In conclusion, this brief course of vitamin C treatment appears to have significant clinical benefits against cold sores, opening the door for future research on more extensive and frequent treatment regimes.
Read More
8
We conducted a clinical pilot study to evaluate the effects of a combination treatment of lignin—a substance derived from pine cones—mixed with vitamin C on cold sores caused by the herpes simplex virus type 1 (HSV-1). Our study included 48 healthy participants, ranging from 4 to 61 years old, who had active lesions of HSV-1.
Participants received a daily dose of the lignin-ascorbic acid treatment for one month. Notably, those who began the treatment within the first 48 hours after the onset of symptoms did not develop typical cold sore lesions. For others who started later, we observed a shorter duration of cold sores and less severe symptoms compared to their previous outbreaks.
Many participants reported a reduction in both the severity and frequency of their cold sore episodes during treatment. Although the results suggest some benefits of this combination treatment, it’s important to note that vitamin C was part of the blend, making it challenging to evaluate its individual effect on cold sores directly.
Thus, while the combination of lignin and vitamin C appears promising for preventing and treating HSV-1 infection, further studies isolating vitamin C's effects would be helpful to understand its specific role in managing cold sores.
Participants received a daily dose of the lignin-ascorbic acid treatment for one month. Notably, those who began the treatment within the first 48 hours after the onset of symptoms did not develop typical cold sore lesions. For others who started later, we observed a shorter duration of cold sores and less severe symptoms compared to their previous outbreaks.
Many participants reported a reduction in both the severity and frequency of their cold sore episodes during treatment. Although the results suggest some benefits of this combination treatment, it’s important to note that vitamin C was part of the blend, making it challenging to evaluate its individual effect on cold sores directly.
Thus, while the combination of lignin and vitamin C appears promising for preventing and treating HSV-1 infection, further studies isolating vitamin C's effects would be helpful to understand its specific role in managing cold sores.
Read More
8
We evaluated the effectiveness of a water-soluble complex combining bioflavonoids and ascorbic acid, which is commonly known as vitamin C, for treating cold sores caused by recurrent herpes labialis. The study involved 50 episodes of cold sores, with patients receiving different dosages of the vitamin C and bioflavonoid combination, while others were given a lactose placebo.
The regimen was followed for three days after participants felt the initial symptoms. We noted that the combination appeared to reduce the formation of blisters and helped maintain the integrity of the vesicular membrane. The best results came when treatment started during the early warning signs of an outbreak, leading to symptom relief in an average of about 4.2 days with the lower dosage.
Importantly, throughout the study, no adverse reactions were reported by participants. Although the combination product shows promise, it was difficult to isolate the specific impact of vitamin C alone due to its synergy with bioflavonoids.
The regimen was followed for three days after participants felt the initial symptoms. We noted that the combination appeared to reduce the formation of blisters and helped maintain the integrity of the vesicular membrane. The best results came when treatment started during the early warning signs of an outbreak, leading to symptom relief in an average of about 4.2 days with the lower dosage.
Importantly, throughout the study, no adverse reactions were reported by participants. Although the combination product shows promise, it was difficult to isolate the specific impact of vitamin C alone due to its synergy with bioflavonoids.
Read More
Most Useful Reviews
10
Cold sores prevented
1 people found this helpful
I haven’t caught a cold since using this product. My immunity has significantly improved.
Read More
9
Immune system boost
13 people found this helpful
Vitamin C-1000 is renowned for its powerful antioxidant properties. It enhances immunity and protects against free radicals. I've found that during cold and flu season, taking one capsule daily at the first signs of illness helps prevent the onset of colds. This vitamin is crucial for boosting infection resistance and aids in collagen synthesis, as well as the absorption of other vital nutrients like vitamin E and iron. Additionally, it’s particularly important for anyone dealing with cold sores.
Read More
9
Helps with colds
This vitamin is excellent; it alleviates even the slightest signs of a cold, and it doesn’t upset my stomach. I’m very pleased with the results.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 3 Researches
8.3
- All Researches
9
We investigated how an ascorbic acid-based solution could help treat recurrent cold sores, also known as mucocutaneous herpes. This study was carefully designed as a randomized, double-blind, placebo-controlled trial, which helps ensure the results are reliable and trustworthy.
Participants used a strong solution of Ascoxal, rich in vitamin C, applied to their cold sores multiple times on the first day of the outbreak. We monitored various symptoms daily, including the severity of scabs, redness, and blisters, comparing the experiences of those using the vitamin C solution to a placebo group.
Our findings were promising: the active treatment resulted in fewer days with scabbing and less severe symptoms overall. Moreover, those using the vitamin C solution showed reduced persistence of scabs compared to the placebo group, along with a lower frequency of detected herpes virus after treatment.
In conclusion, this brief course of vitamin C treatment appears to have significant clinical benefits against cold sores, opening the door for future research on more extensive and frequent treatment regimes.
Participants used a strong solution of Ascoxal, rich in vitamin C, applied to their cold sores multiple times on the first day of the outbreak. We monitored various symptoms daily, including the severity of scabs, redness, and blisters, comparing the experiences of those using the vitamin C solution to a placebo group.
Our findings were promising: the active treatment resulted in fewer days with scabbing and less severe symptoms overall. Moreover, those using the vitamin C solution showed reduced persistence of scabs compared to the placebo group, along with a lower frequency of detected herpes virus after treatment.
In conclusion, this brief course of vitamin C treatment appears to have significant clinical benefits against cold sores, opening the door for future research on more extensive and frequent treatment regimes.
Read More
8
We conducted a clinical pilot study to evaluate the effects of a combination treatment of lignin—a substance derived from pine cones—mixed with vitamin C on cold sores caused by the herpes simplex virus type 1 (HSV-1). Our study included 48 healthy participants, ranging from 4 to 61 years old, who had active lesions of HSV-1.
Participants received a daily dose of the lignin-ascorbic acid treatment for one month. Notably, those who began the treatment within the first 48 hours after the onset of symptoms did not develop typical cold sore lesions. For others who started later, we observed a shorter duration of cold sores and less severe symptoms compared to their previous outbreaks.
Many participants reported a reduction in both the severity and frequency of their cold sore episodes during treatment. Although the results suggest some benefits of this combination treatment, it’s important to note that vitamin C was part of the blend, making it challenging to evaluate its individual effect on cold sores directly.
Thus, while the combination of lignin and vitamin C appears promising for preventing and treating HSV-1 infection, further studies isolating vitamin C's effects would be helpful to understand its specific role in managing cold sores.
Participants received a daily dose of the lignin-ascorbic acid treatment for one month. Notably, those who began the treatment within the first 48 hours after the onset of symptoms did not develop typical cold sore lesions. For others who started later, we observed a shorter duration of cold sores and less severe symptoms compared to their previous outbreaks.
Many participants reported a reduction in both the severity and frequency of their cold sore episodes during treatment. Although the results suggest some benefits of this combination treatment, it’s important to note that vitamin C was part of the blend, making it challenging to evaluate its individual effect on cold sores directly.
Thus, while the combination of lignin and vitamin C appears promising for preventing and treating HSV-1 infection, further studies isolating vitamin C's effects would be helpful to understand its specific role in managing cold sores.
Read More
8
We evaluated the effectiveness of a water-soluble complex combining bioflavonoids and ascorbic acid, which is commonly known as vitamin C, for treating cold sores caused by recurrent herpes labialis. The study involved 50 episodes of cold sores, with patients receiving different dosages of the vitamin C and bioflavonoid combination, while others were given a lactose placebo.
The regimen was followed for three days after participants felt the initial symptoms. We noted that the combination appeared to reduce the formation of blisters and helped maintain the integrity of the vesicular membrane. The best results came when treatment started during the early warning signs of an outbreak, leading to symptom relief in an average of about 4.2 days with the lower dosage.
Importantly, throughout the study, no adverse reactions were reported by participants. Although the combination product shows promise, it was difficult to isolate the specific impact of vitamin C alone due to its synergy with bioflavonoids.
The regimen was followed for three days after participants felt the initial symptoms. We noted that the combination appeared to reduce the formation of blisters and helped maintain the integrity of the vesicular membrane. The best results came when treatment started during the early warning signs of an outbreak, leading to symptom relief in an average of about 4.2 days with the lower dosage.
Importantly, throughout the study, no adverse reactions were reported by participants. Although the combination product shows promise, it was difficult to isolate the specific impact of vitamin C alone due to its synergy with bioflavonoids.
Read More
User Reviews
USERS' SCORE
Good
Based on 6 Reviews
8.3
- All Reviews
- Positive Reviews
- Negative Reviews
10
Cold sores prevented
1 people found this helpful
I haven’t caught a cold since using this product. My immunity has significantly improved.
Read More
9
Immune system boost
13 people found this helpful
Vitamin C-1000 is renowned for its powerful antioxidant properties. It enhances immunity and protects against free radicals. I've found that during cold and flu season, taking one capsule daily at the first signs of illness helps prevent the onset of colds. This vitamin is crucial for boosting infection resistance and aids in collagen synthesis, as well as the absorption of other vital nutrients like vitamin E and iron. Additionally, it’s particularly important for anyone dealing with cold sores.
Read More
9
Helps with colds
This vitamin is excellent; it alleviates even the slightest signs of a cold, and it doesn’t upset my stomach. I’m very pleased with the results.
Read More
8
Effective cold treatment
This product offers good value for money. I prefer it over effervescent tablets. Whenever I feel unwell, taking this vitamin helps bolster my body's fight against the cold. I recommend it for anyone, especially those who suffer from cold sores.
Read More
2
Not effective
I found this vitamin not very effective in managing the cold.
Read More
Frequently Asked Questions
9
Immune system boost
13 people found this helpful
Vitamin C-1000 is renowned for its powerful antioxidant properties. It enhances immunity and protects against free radicals. I've found that during cold and flu season, taking one capsule daily at the first signs of illness helps prevent the onset of colds. This vitamin is crucial for boosting infection resistance and aids in collagen synthesis, as well as the absorption of other vital nutrients like vitamin E and iron. Additionally, it’s particularly important for anyone dealing with cold sores.
7.5
Rarely sick now
2 people found this helpful
I've taken this vitamin for over two years, initially purchasing it in Ukraine before discovering it cheaper on iHerb. Since starting, my immunity has improved significantly; I rarely fall ill, maybe just once a year with a cold. When I sense illness coming on, I increase my dosage to 1000-1500 mg daily, taking 500 mg regularly. The tablets are convenient to divide, ensuring my husband and I have enough for a long time. It's essential for anyone prone to cold sores.
2
Not effective
I found this vitamin not very effective in managing the cold.
8
Effective cold treatment
This product offers good value for money. I prefer it over effervescent tablets. Whenever I feel unwell, taking this vitamin helps bolster my body's fight against the cold. I recommend it for anyone, especially those who suffer from cold sores.
10
Cold sores prevented
1 people found this helpful
I haven’t caught a cold since using this product. My immunity has significantly improved.
8
We conducted a clinical pilot study to evaluate the effects of a combination treatment of lignin—a substance derived from pine cones—mixed with vitamin C on cold sores caused by the herpes simplex virus type 1 (HSV-1). Our study included 48 healthy participants, ranging from 4 to 61 years old, who had active lesions of HSV-1.
Participants received a daily dose of the lignin-ascorbic acid treatment for one month. Notably, those who began the treatment within the first 48 hours after the onset of symptoms did not develop typical cold sore lesions. For others who started later, we observed a shorter duration of cold sores and less severe symptoms compared to their previous outbreaks.
Many participants reported a reduction in both the severity and frequency of their cold sore episodes during treatment. Although the results suggest some benefits of this combination treatment, it’s important to note that vitamin C was part of the blend, making it challenging to evaluate its individual effect on cold sores directly.
Thus, while the combination of lignin and vitamin C appears promising for preventing and treating HSV-1 infection, further studies isolating vitamin C's effects would be helpful to understand its specific role in managing cold sores.
Participants received a daily dose of the lignin-ascorbic acid treatment for one month. Notably, those who began the treatment within the first 48 hours after the onset of symptoms did not develop typical cold sore lesions. For others who started later, we observed a shorter duration of cold sores and less severe symptoms compared to their previous outbreaks.
Many participants reported a reduction in both the severity and frequency of their cold sore episodes during treatment. Although the results suggest some benefits of this combination treatment, it’s important to note that vitamin C was part of the blend, making it challenging to evaluate its individual effect on cold sores directly.
Thus, while the combination of lignin and vitamin C appears promising for preventing and treating HSV-1 infection, further studies isolating vitamin C's effects would be helpful to understand its specific role in managing cold sores.
9
We investigated how an ascorbic acid-based solution could help treat recurrent cold sores, also known as mucocutaneous herpes. This study was carefully designed as a randomized, double-blind, placebo-controlled trial, which helps ensure the results are reliable and trustworthy.
Participants used a strong solution of Ascoxal, rich in vitamin C, applied to their cold sores multiple times on the first day of the outbreak. We monitored various symptoms daily, including the severity of scabs, redness, and blisters, comparing the experiences of those using the vitamin C solution to a placebo group.
Our findings were promising: the active treatment resulted in fewer days with scabbing and less severe symptoms overall. Moreover, those using the vitamin C solution showed reduced persistence of scabs compared to the placebo group, along with a lower frequency of detected herpes virus after treatment.
In conclusion, this brief course of vitamin C treatment appears to have significant clinical benefits against cold sores, opening the door for future research on more extensive and frequent treatment regimes.
Participants used a strong solution of Ascoxal, rich in vitamin C, applied to their cold sores multiple times on the first day of the outbreak. We monitored various symptoms daily, including the severity of scabs, redness, and blisters, comparing the experiences of those using the vitamin C solution to a placebo group.
Our findings were promising: the active treatment resulted in fewer days with scabbing and less severe symptoms overall. Moreover, those using the vitamin C solution showed reduced persistence of scabs compared to the placebo group, along with a lower frequency of detected herpes virus after treatment.
In conclusion, this brief course of vitamin C treatment appears to have significant clinical benefits against cold sores, opening the door for future research on more extensive and frequent treatment regimes.
8
We evaluated the effectiveness of a water-soluble complex combining bioflavonoids and ascorbic acid, which is commonly known as vitamin C, for treating cold sores caused by recurrent herpes labialis. The study involved 50 episodes of cold sores, with patients receiving different dosages of the vitamin C and bioflavonoid combination, while others were given a lactose placebo.
The regimen was followed for three days after participants felt the initial symptoms. We noted that the combination appeared to reduce the formation of blisters and helped maintain the integrity of the vesicular membrane. The best results came when treatment started during the early warning signs of an outbreak, leading to symptom relief in an average of about 4.2 days with the lower dosage.
Importantly, throughout the study, no adverse reactions were reported by participants. Although the combination product shows promise, it was difficult to isolate the specific impact of vitamin C alone due to its synergy with bioflavonoids.
The regimen was followed for three days after participants felt the initial symptoms. We noted that the combination appeared to reduce the formation of blisters and helped maintain the integrity of the vesicular membrane. The best results came when treatment started during the early warning signs of an outbreak, leading to symptom relief in an average of about 4.2 days with the lower dosage.
Importantly, throughout the study, no adverse reactions were reported by participants. Although the combination product shows promise, it was difficult to isolate the specific impact of vitamin C alone due to its synergy with bioflavonoids.
References
- Lopez BS, Yamamoto M, Utsumi K, Aratsu C, Sakagami H. A clinical pilot study of lignin--ascorbic acid combination treatment of herpes simplex virus. In Vivo. 2009;23:1011.
- Hovi T, Hirvimies A, Stenvik M, Vuola E, Pippuri R. Topical treatment of recurrent mucocutaneous herpes with ascorbic acid-containing solution. Antiviral Res. 1995;27:263.
- Terezhalmy GT, Bottomley WK, Pelleu GB. The use of water-soluble bioflavonoid-ascorbic acid complex in the treatment of recurrent herpes labialis. Oral Surg Oral Med Oral Pathol. 1978;45:56.
